Category: sygmlvwnhhlu

Large Tanker Orderbook Not as Scary as It Looks

first_imgzoom Based on the delivery schedule of the current orderbook, deliveries of new tankers in 2017 will reach the highest level since 2009, however, Poten & Partners argues that the orderbook may not be as scary as it looks.While, it is difficult to see how the market can absorb such a large orderbook without further pressure on tanker rates and prices, there may be some mitigating factors to consider.The Suezmaxes stand out on the crude tanker side, and if all Suezmaxes that are scheduled for delivery this year leave the shipyards on time, a total of 10.1 million dwt would be added to the fleet, well above the 2009 record of 7.1 million dwt, and two and a half times total 2016 deliveries.The recent high-water mark for VLCCs was 2011, when 65 new units of 20.1 million dwt hit the water. This year, the yards are scheduled to deliver 15.9 million dwt, while Aframax and LR2 deliveries in this year would reach 9.4 million dwt in total. Deliveries for the Panamax/LR1 segment are expected to stand at 2.4 million dwt in 2017.In the smaller product carrier segments, the orderbook for delivery in 2017 is more moderate, compared to earlier years.A total of 77 MRs are scheduled to join the fleet in 2017, while the Handysize vessels seems to have fallen out of favor as only 18 are expected to be delivered during the year.However, the main mitigating factor when considering the above fleet statistics is that there can be significant discrepancies between scheduled and actual deliveries, especially in periods with a challenging rate environment.“Delivery delays and order cancellations picked up considerably after the tanker market dropped in 2009,” Poten & Partners said, adding that VLCCs have the highest average delivery ratio of 80%, ranging from a high of 100% in 2006/2008 to a low of 53% in 2013.Product carrier orderbook statistics appear less reliable and these tankers a low average delivery ratio of around 50%. Even during the strong freight markets of 2005-2008, only 65% of the vessels that were reportedly on order were delivered.“Based on the historical variability of vessel deliveries and its apparent correlation with the freight market, 25-40% of the crude oil tanker orderbook and up to 50% of the product carriers scheduled for 2017 might not be delivered this year. The orderbook remains high, but the outlook for tanker supply in 2017 is better than a cursory look suggests,” Poten & Partners informed.last_img read more

NordLB Closes Sale of EUR 26 Bn Shipping Loan Portfolio

first_imgzoomIllustration. Image Courtesy: Pixabay under CC0 Creative Commons license Germany’s Norddeutsche Landesbank (Nord/LB) has completed the sale of a EUR 2.6 billion shipping loan portfolio.An affiliate of global alternative investment manager Cerberus Capital Management took over the portfolio, which comprises of a total of 263 ships with a non-performing loan (NPL) portion of some 90%.The so-called “Big Ben” transaction was closed on April 9, in accordance with the signing of the purchase agreement in February 2019. The parties agreed to maintain confidentiality about the terms of the transaction.Upon completion of the sale, the bank’s NPL portfolio, which amounted to EUR 7.5 billion at the end of 2018, was reduced to around EUR 4.9 billion.The portfolio, that groups together the legacy problem assets from ship financing, should be almost completely run off by the end of 2019, Thomas Bürkle, Chairman of Nord/LB, earlier said.last_img read more

Free Guided Tour of Protected Area

first_imgNova Scotians will have the opportunity to see rugged beauty, rare or unusual plant life, and protected coastal barrens during a tour of the Duncans Cove Nature Reserve on Saturday, Aug. 12. The Department of Environment and Labour is offering the free guided tour of Duncans Cove for anyone interested in learning about the reserve. Two tours are scheduled for the day, the first will depart at 10 a.m., and second at 2:30 p.m. “This is the sixth nature reserve and wilderness tour in Nova Scotia this year,” said Mark Parent, Minister of Environment and Labour. “Support for the tours has been tremendous and we are pleased to continue offering them throughout the fall and winter months.” Overlooking outer Halifax Harbour, the Duncans Cove tour will allow participants to explore footpaths above the shore and across high granite ridges. The rugged coastal barrens of Duncans Cove are home to many species that are adapted to wind, fog and thin soils. For more information and a map showing the guided tour location, contact Oliver Maass at 902-424-2123, or see the Department of Environment and Labour website at .last_img read more

New registered charity in North Peace to assist lowincome seniors with healthrelated

first_imgFORT ST. JOHN, B.C. – A new registered charity to assist low-income seniors with health-related costs has started up in the North Peace.The North Peace Seniors Mouth-Eye-Foot Care Foundation is a registered charity that aims to assist seniors with a low income to help cover the associated cost of dental, eye, and foot care.According to the Foundation, applicants are received and then vetted by an impartial social worker who is qualified to ascertain annual income. In order to provide these much-needed services to seniors, the Foundation is currently looking for financial support from the community.If you wish to get in contact, and for more information, you can call the Foundation at 250-787-0218 or email information can also be found on the North Peace Seniors Mouth-Eye-Foot Care Foundation’s website or Facebook page.last_img read more

Via Rail and Air Transat join forces to streamline service schedules

MONTREAL — Air Transat and VIA Rail Canada are streamlining their service schedules in hopes of encouraging travellers to buy tickets that combine both modes of transport.In a news release this week, the companies said they’re hoping the partnership will encourage Canadians to take advantage of both air and rail travel.Air Transat said in June that it is looking to reduce costs and differentiate its offering after plans to turn a profit this year were dashed by a large loss in the key winter period.The company posted a loss of $13.2-million, or 35 cents per share, in the second quarter.[np-related]The winter period was the fourth quarterly loss in a row for the company, which operates a variety of vacation and travel businesses including the Air Transat airline, packaged holiday operators and travel agencies.“Thanks to this partnership, Transat is making vacations even more accessible to Canadians and is allowing its customers to expand upon travel destination opportunities by conducting a rail transfer to one of its main departure cities,” said Joseph Adamo, vice-president of marketing at Transat Canada.VIA Rail says the announcement is the latest in a series of measures the company is undertaking to modernize passenger rail.“This announcement is in line with VIA Rail’s strategy of creating synergy among carriers in order to enhance the client experience and facilitate intermodal travel”, said VIA Rail president and CEO Marc Laliberte.“Today’s announcement is driven by our ongoing effort to improve our services. This strategy demonstrates that by working together, passenger carriers can increase the mobility of all Canadians while increasing the number of passengers for all methods of transport.” read more

Week in Brussels – week ending Friday 29 May 2015

DOWNLOAD1.     France and Germany agree to closer EU ties2.     ACEA – Commercial vehicle registrations up 12.2%3.     EU considering mandatory corporate tax base4.     European Commission proposes draft Budget 20165.     INTA adopts report on TTIP6.     Week aheadClick to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)

Proposal deadline approaching for Student Leadership Summit

It’s not too late to claim a place at the summit.Brock students are encouraged to submit workshop and TED Talk proposals for the Jan. 13 Niagara Student Leadership Summit.The daylong event aims to provide hands-on learning and practical experience for students by engaging them in presentations and workshops that will encourage skill development and personal and professional growth.“We are excited to see Brock students embrace the opportunity to present to the community and to experience leadership first-hand,” said Celyn Talaue, Student Life and Community Experience’s leadership development student assistant.TED Talk-style presentations, each meant to be powerful and 10 to 15 minutes in length, will take place in Sean O’Sullivan Theatre, with speakers each highlighting a different type of leadership.Workshops will focus on the application of leadership skills to everyday life. They will take place in Thistle Complex classrooms and run for 45 to 70 minutes.The deadline to apply to present a workshop or TED Talk is Friday, Nov. 24.To submit a proposal or to register to participate in the summit, visit ExperienceBU. read more

Philip Pullman to name character after teenage Grenfell Tower victim as auction

first_imgThis is happening on the Philip Pullman ‘name a character’ lot and I’m now sobbing uncontrollably. #authorsforgrenfell— Laura Steven (@LauraMSteven) June 26, 2017 Inspired by this, many people have added money to the pledge, to ensure the character is named after Nur Huda. The character will be in the new novel from the acclaimed author, the second in the ‘Book of Dust’ series.Philip Pullman wrote: “This book will follow the first part of THE BOOK OF DUST, ‘La Belle Sauvage’, which will be published in October this year. The second part (not yet titled) will follow next year. The right to name a character doesn’t guarantee that he or she will be good, bad, beautiful or otherwise, but it will be a speaking role with a part to play in the plot.”People have now raised over £17,000, and the amount is going up all the time.No one has asked for another name since the name Nur Huda was suggested. “Please outbid me by lots though – it’s an important cause”. Nur Huda el-Wahabi Credit:Facebook Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily  Front Page newsletter and new  audio briefings.center_img Nur Huda el-Wahabi  He said: “I expect this will go for a lot more (and I hope it does) but here goes: £1,500.”If this is still the leading bid on Tuesday, I’d like to call the character Nur Huda el-Wahabi.”The real Nur Huda was an ex-pupil of mine who lived in Grenfell Tower and didn’t make it out of the building that night.”A life that was so full of promise has been cut short in the most terrible way.”As well as raising some money, this would mean her name would live on. Plus Nur Huda is a pretty cool name for a character. Philip Pullman is likely to name one of the characters in his newest book after one of the young victims believed dead after the Grenfell Tower blaze following an auction campaign which has raised thousands of pounds.The Authors for Grenfell campaign is raising money for the families affected by the fire as authors auction off literature-based prizes.Philip Pullman has offered to give a name of the winner’s choice to one of the characters in his latest book.A teacher of 15-year-old Nur Huda el-Wahabi, who is believed to have died in the fire along with her family, pledged £1,500 to secure her name.last_img read more

Chess contest offers free tickets to women amid long hard struggle to

Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily  Front Page newsletter and new  audio briefings. A London chess competition is offering free tickets to women players, in a “long hard struggle” to close the gender gap.While men pay £60 to be allowed to compete in the London Chess Classic, women and under-25s are granted free admission. Malcolm Pein, the organiser of the competition and Telegraph chess columnist, said he was “looking forward” to when he no longer had to offer women free admission, but that “it will be a long and hard struggle.”He added: “We had a record attendance for the women’s championship in August. We made the competition more female friendly in a variety of ways.”You  have women organising the event, you increase the prize money”One of the other things we do in the London Chess Classic is encourage women to be chess referees as well as players. We have far more women arbeiters, that helps.”Jovanka Houska, Britain’s number one female chess player, told The Telegraph: “I think it’s a great thing to get more women involved in chess tournaments, we have a big problem with women playing so anything that’s done to get the numbers to increase gets my vote.”I would encourage more investment from clubs, clubs are not necessarily making it fun for women to play – there’s too much focus on competition but not enough on social life.”Some of the best nights I had when in a club was almost a party setting. I’ve seen it done in America, they should have ladies only nights.”She said that the gap is “particularly bad” in England, arguing: “there’s a lot of institutionalised sexism going on. Sexism is so ingrained people don’t know there’s something going on. The standard in the UK of the women is a lot worse than of the boys and the men.”Mr Pein agreed, adding: “The general participation rate in chess tournaments is extremely low, it’s just dreadful in this country and something needs to be done about it.”There isn’t enough data to say but in other countries in the world where I go to chess tournaments, in France the rates are way beter for example, we are much worse.” read more

La fondation Nicolas Hulot quitte le Grenelle de lenvironnement

first_imgLa fondation Nicolas Hulot quitte le Grenelle de l’environnementFrance – Au lendemain de l’annonce du report de la taxe carbone, la fondation Nicolas Hulot a décidé de suspendre sa participation aux groupes de travail chargés de travailler sur le projet de loi du second Grenelle de l’environnement et de la mer. Furieux de la décision du gouvernement, qui préfère attendre la mise en place d’une taxe européenne pour instaurer la contribution climat-énergie en France, Nicolas Hulot a annoncé que sa fondation ne participerait pas aux prochains travaux du Grenelle de l’environnement.”L’abandon pur et simple de la taxe carbone, alors qu’un processus de concertation était en cours, est symptomatique d’un net recul de la classe politique qui, à droite comme à gauche, n’a pas pris la mesure des enjeux écologiques, et les considère essentiellement comme une variable d’ajustement politique” estime la fondation, quand le ministre de l’Environnement Jean-Louis Borloo assure que la décision de Nicolas Hulot n’est rien d’autre qu’un “moment d’énervement”.Bruno Le Maire, ministre de l’Agriculture, appelle lui aussi l’initiateur du pacte écologique signé par Nicolas Sarkozy lors de la dernière campagne présidentielle à revenir à la raison. “J’ai eu l’occasion de rencontrer Nicolas Hulot à plusieurs reprises, et sa participation est utile […]. On a toujours intérêt à écouter les avis des organisations non gouvernementales, des associations écologistes” a-t-il estimé sur Europe 1.La suspension de la participation de la fondation au Grenelle a suscité de très nombreuses autres réactions. Alain Juppé a ainsi assuré comprendre la réaction de Nicolas Hulot face au regain de l’écolo-scepticisme “alors que les problèmes sont toujours devant nous”. De son côté, Jean-François Copé, président du groupe UMP à l’Assemblée, a affirmé regretter la décision de l’écologiste, soulignant que “ce serait une erreur énorme de réduire” le Grenelle de l’environnement à la seule taxe carbone.Le 30 mars 2010 à 16:45 • Emmanuel Perrinlast_img read more

John Cena Big Cass and Enzo Amore vs The Club and Becky

first_img Vin Diesel and John Cena share ‘intense’ scene Now Playing Up Next Adam Martin RELATED ARTICLESMORE FROM AUTHOR Comments are closed. Enzo Amore Former WWE star Big Cass reportedly has incident at WrestlePro Event in New Jersey 1 COMMENT Now Playing Up Next Now Playing Up Next WWE Lists The Shields Top 10 Wins Now Playing Up Next WWE Wrestler Enzo Amore Kicked Off Flight Pinterest July 5, 2016 at 1:03 am Joey Janela comments on backstage incident with Big Cass at WrestlePro Event I really hope The (Bullet) Club wins at BattleGround. Twitter Videos Articles Now Playing Up Next Big Cass WWE Superstar John Cena announced as part of cast for Suicide Squad Sequel Videos Articles John Cena, Big Cass and Enzo Amore vs. The Club in a six man tag team match and Becky Lynch vs. Natalya has been added to the card for WWE Battleground on July 24. These matches were announced live during RAW on Monday night.JUST ANNOUNCED: At #WWEBattleground, @JohnCena teams with #EnzoAndCass vs. #TheClub! #RAW— WWE (@WWE) July 5, 2016Here is the updated card for WWE Battleground.WWE Championship – Triple Threat MatchDean Ambrose (c) vs. Seth Rollins vs. Roman ReignsKevin Owens vs. Sami ZaynJohn Cena, Big Cass and Enzo Amore vs. The ClubBecky Lynch vs. will have live coverage of WWE Battleground 2016 on Sunday, July 24.Recommended videosPowered by AnyClipWWE Wrestler Enzo Amore Kicked Off FlightVideo Player is loading.Play VideoPauseUnmuteDuration 0:32/Current Time 0:02Loaded: 100.00%0:02Remaining Time -0:30 FullscreenUp NextThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Replay the list WhatsApp Google+ Cameron Huff Facebook Why Total Divas Didnt Change Their Name After WWE Rebranded Becky Lynch `WWE 24` Documentary Premier Date Announcedlast_img

As charges go up visits to state parks decline

first_imgState parks shuffle local staffOLYMPIA — Fewer people are visiting Washington State Parks since the introduction of parking pass charges last July.When the state Legislature slashed parks funding last year, the Washington State Parks and Recreation Commission adopted the Discover Pass to maintain operations. The pass, which is required for vehicle access to state parks, cost s$10 for a single visit or $30 for the year. There are also transaction and dealer fees if the passes are purchased at a licensed dealer, by phone or online.These charges may be proving too much for park enthusiasts. While nearly 6.8 million people attended state parks during the day in July 2010, only 5.6 million visited in July 2011, after the pass became mandatory.If these attendance rates and the revenue connected to them don’t turn around quickly, the parks could fall into disrepair.The local outlook is a little brighter. Despite statewide trends, visits to Battle Ground Lake State Park are up. More than 41,000 people made a day trip to the park in July 2011, after the Discover Pass was required. This was up from about 27,000 day visitors in July 2010.Pete Mayer, director of Vancouver-Clark Parks and Recreation, said Battle Ground Lake State Park is a popular destination because it provides a wide range of activities near an urban center.Attendance rates for parks run by the city and county have jumped as well, he said. He attributed the rise in visitors to the recession — more families are taking “stay-cations” instead of traveling out of state.last_img read more

Serco staff at Barts Health NHS Trust strike over pay dispute

first_imgMembers of trade union Unite who work for public services organisation Serco and are based at hospitals within Barts Health NHS Trust are taking strike action in a dispute over pay.Cleaners, domestic staff, porters, and security staff based across four London hospitals in the Barts Health NHS Trust began 48 hours of strike action yesterday (Tuesday 4 July 2017) after 99% of Unite members who took part in the strike ballot voted in favour of strike action.The dispute revolves around a proposed pay increase. Unite members employed by Serco are seeking a £0.30 an hour wage increase.Serco invited Unite to negotiations with conciliation and arbitration service Acas on 28 June 2017, but the trade union claims that Serco failed to bring a new proposal to the discussions.The strike involves Serco staff at Mile End Hospital, Royal London Hospital, St Bartholomew’s Hospital, and Whipps Cross University Hospital. The current strike action will end at 6am on Thursday 6 July.Serco staff who are members of Unite are also planning a seven-day strike starting on Tuesday 11 July, followed by a two-week strike from Tuesday 25 July. Further strike action will also be planned for August and September.Phil Mitchell, contract director at Serco, said: “We believe strongly in ensuring our dedicated team are rewarded fairly, which is why we agreed with the Trust to pay all our team members a minimum of the London living wage from day one. This resulted in an increase in pay for over 230 team members and benefited over 110 permanent staff by an average of 3.5%. For those team members on higher salaries, we have offered a pay increase for this year which is in line with that for NHS staff.“We are determined to ensure that Unites action does not impact on patients. We have robust plans in place aimed at ensuring we can continue to support the Trust’s hospitals to operate as normal during the planned action.”Gloria Sindall, regional officer at Unite, said: “[Employees] across four London hospitals will be taking strike action this week in a battle against low pay. Cleaners, porters and security staff have seen their real living standards drop year on year.“Workers are now demanding a 30p per hour wage increase. Serco made over £80 million in profit last year but managers are refusing to share these earnings fairly and protect the living standards of the workers.“Rather than try to settle this dispute the private contractor Serco wasted valuable time by offering absolutely nothing new for the workforce at talks with Acas last week. Unite members are fed up and are preparing for a series of strikes to demand a fair and proper pay rise which recognises the contribution they make to Serco and to Barts.”A spokesperson at Barts Health NHS Trust added: “We have been working closely with both sides to find a resolution to this dispute, urging them to seek a solution through the mediation service Acas.“Contingency plans are in place to minimise any disruption to staff and patients at our hospitals. All patient care at each of our hospitals will continue and we advise patients to attend their hospital appointments as normal.”last_img read more

Hyderabad to receive heavy rainfall in next 24 hours

first_imgIncessant rains lash Hyderabad in the next 24 hours, according to the Indian Meteorological Department (IMD). As the monsoon has covered the Telangana entirely, the state will witness heavy rainfall for the next three days The cause of rainfall is attributed to the formation of pressure over the East and West region of Bay of Bengal covering Rajasthan and Chhattisgarh. On Saturday, Nagarkurnool district in Telangana witnessed the highest rainfall of 6 cm. On Friday, the Hyderabad city received downpour which caused traffic snarls and the low lying areas were flooded with rain water. The rains are expected to lash Telangana constantly for two days in the next 24 hours.last_img read more

CDSL IPO oversubscribed 169 times poised for spectacular listing

first_imgA man looks at a screen displaying news of markets update inside the Bombay Stock Exchange (BSE) building in Mumbai, June 20, 2016.Reuters fileShares of Central Depository Services (India) Limited, or CSDL, the depository arm of BSE, are likely to get a spectacular listing after the Rs 524-crore issue closed with 169 times’ oversubscription on June 21, the last day of the initial public offering (IPO).Data available with stock exchanges as of 5.30 PM on June 21 showed that bids were received for almost 420 crore shares, setting the stage for a blockbuster debut on the stock exchanges. Mumbai-based CDSL issued 3.52 crore shares in the price band of Rs 145 to 149 per equity share; 7 lakh shares were reserved for eligible employees and 1.03 crore shares for anchor investors from whom the company raised Rs 154 crore, leaving 2.48 crore shares for the public.The IPO was an offer for sale by existing investors — up to 27,217,850 equity shares by BSE Limited; up to 4,775,000 equity shares by State Bank of India; up to 2,174,358 equity shares by Bank of Baroda and up to 1,000,000 equity shares by The Calcutta Stock Exchange.The post-issue shareholding of promoters will stand at 24 percent from the current 50 percent.Here are the highlights of CDSL and its IPO (according to Angel Broking, Centrum Broking):CDSL has wide source of revenues, 35 percent from the annual issuer charges (which is recurring in nature) and 21 percent from transactions having some correlation with volumes in the markets. Another 13 percent comes from online data charges.As the capital markets have remained buoyant, there has been an increasing trend of new listings, and thus, CDSL has generated 11 percent of its revenues from the IPO/ Corporate action charges. Hence, broadly speaking, the revenue base of CDSL is quite diversified.CDSL has a market share of about 43 percent in demat accounts.The number of demat accounts at CDSL has grown at a CAGR of 8.6 percent over FY2011-17 to 12.3 millionn, compared to 5.1 percent for (rival) NSDL over the same period, to 15.6 million.The company earned a net profit of Rs 86 crore on operating income of Rs 146 crore in 2016-17 in comparison to Rs 91 crore net profit and Rs 123 crore in the preceding fiscal.The company is debt-free cash rich (cash and investment of Rs 551 crore as on Mar’17). The company has healthy return ratios (FY17 – RoE 17.3 percent, RoCE 22.3 percent and RoIC 27.9 percent). Its stable business and steady revenue growth has allowed them to consistently pay dividends (last 3 years average 40 percent pay out).last_img read more

Russia wont support any UN move to pressure Myanmar

first_imgRohingya refugee. File PhotoRussia has reiterated its position to resolve Rohingya crisis through “bilateral negotiations” saying it will not support any resolution in the United Nations Security Council (UNSC) to put pressure on Myanmar engaging the UN.”China has its own policy. Our position is very similar to Chinese one that this issue (Rohingya) should be settled through negotiations. It’s a bilateral issue,” said Russian ambassador to Bangladesh Alexander I. Ignatov at a seminar in the city on Thursday, reports UNB.The UNSC is thinking of fresh actions to push Myanmar to work with the UN to address the Rohingya crisis. Russia and China have so far boycotted discussions on a British-drafted resolution.Referring to the UK-initiated draft resolution on finding sort of comprehensive solution to Rohingya crisis, Ambassador Ignatov said they do not support 1 percent of that kind of particular draft resolution. “I don’t believe it’ll be adopted.”Asked why Russia has failed to extend support in the UNSC and beyond on Rohingya issue when Russia never faltered in extending support to Bangladesh, the Ambassador said, “Russia hasn’t failed in this regard. It’s completely wrong to say so.”He explained further saying they have different approach compared to some other countries and said putting pressure on Myanmar, they believe, will create complexities as Bangladesh and Myanmar signed bilateral agreement on repatriation of Rohingyas.The Russian ambassador said they believe in proper implementation of the bilateral agreement on repatriation.He, however, said Rohingyas should be allowed to go back to their place of origin and of course the situation for them should be humane.Bangladesh and Myanmar formed the Joint Working Group (JWG) in December 2017 to start the repatriation of around 900,000 Rohingyas who fled a brutal military crackdown in August 2017.However, the Rohingya repatriation plan, as agreed by Bangladesh and Myanmar to begin in mid-November this year, failed.The seminar on ’47 Years of Friendship: Bangladesh-Russia Relations’ was held at Bangladesh Institute of International and Strategic Studies (BIISS) on Thursday.Foreign secretary M Shahidul Haque attended the seminar as the chief guest with president of Bangladesh-Russia Friendship Society AAMS Arefin Siddique in the chair.last_img read more

Rice Professor Spurs Students To Create HighImpact Medical Designs For LowResource African

first_imgJeff Fitlow/Rice UniversityIn her lab at Rice, bioengineer Rebecca Richards-Kortum is developing a new kind of high-resolution microendoscope, which could reduce the need for expensive biopsies to diagnose esophageal cancer.A faculty member at Rice University, Rebecca Richards-Kortum, won the country’s highest honor this year from the American Institute for Medical and Biomedical Engineering.She is the first woman to win the prestigious prize, known as the Pierre Galletti Award, in its 17-year history.  Richards-Kortum, 52, has inspired a generation of Rice students through her teaching and mentorship, particularly at the Rice 360° Institute for Global Health. The program allows students to engineer prototypes to solve real-world health problems in low-income regions of the world, such as sub-Saharan Africa.One of the student teams developed an alternative device to help premature infants breathe, she tells Health and Science reporter Carrie Feibel. The device, known as “bubble CPAP” (continuous positive airway pressure), can cost a U.S. neonatal unit up to $6,000.Rice 360°/Rice UniversityNeonatal nurse Florence Mwenifumbo monitors a newborn that is receiving bubble CPAP treatment at Queen Elizabeth Central Hospital in Blantyre, Malawi.But the student’s design model cost much less, and could handle the harsh environmental conditions of countries like Malawi, where it underwent clinical trials in hospitals. It’s now manufactured by Hadleigh Health Technologies in California and sold as Pumani bCPAP.“It’s a very, very simple idea where you blow a mix of air and oxygen into a baby’s nose at constant pressure,” said Richards Kortum. “What our students did is they designed a very simple device that uses two aquarium pumps as the flow-driver. It’s a very inexpensive consumer product, that’s designed to run forever.”Tommy LaVergne/Rice UniversityPumani, an award-winning low-cost device that Rice University students invented to help premature babies in Malawi breathe more easily, will be rolled out to teaching hospitals in Tanzania, Zambia and South Africa, thanks to a $400,000 innovation award from pharmaceutical giant GlaxoSmithKline (GSK) and London-based charity Save the Children.Other devices developed by Richards-Kortum and her students are also in various stages of development.Richards-Kortum also spoke about the significance of the Galetti award and what motivates young women and students of color to pursue careers science, math and engineering.“When you connect the dots between the study of science and engineering and its impact on solving socially important problems, you attract a more diverse group of students,” Richards-Kortum said,“and they are more likely to persist and graduate with a major in engineering and science.”Hear the full interview above. 00:00 /03:31 To embed this piece of audio in your site, please use this code: Share Listen Xlast_img read more

31 of Our Favorites From Inktober 2016

first_imgOne of my favorite things about October is getting to see all of my very talented pals participate in Inktober. Inktober is a wonderful time of year where artists all over the world challenge themselves to create a new piece of work every day in October. Originally it was created as a way to help improve skills, develop good habits, promote positive growth in the community. But really all can participate, “Anyone can do InkTober, just pick up a pen and start drawing.”The rules are simple:1) Make a drawing in ink (you can do a pencil under-drawing if you want).2) Post it online3) Hashtag it with #inktober and #inktober20164) RepeatHere are 31 of my favorites from this year!View as: One Page Slides1. Lydia Deetz, BeetlejuiceSibylline Meynet – @Sibylline_Msibylline-art.blogspot.com2. K2SO, Star Wars: Rogue OneNick Brokenshire – Wolf & ArtistJeff Stokely – @JeffStokelyjeffstokely.com4. Puppy PilotJames Harren – @JamesHarren1felixcomicart.com5. Black WidowChris Jonson – @ChrisJInFictionchrisjohnsoninfiction.tumblr.com6. This Island EarthWilfredo Torres – @mightyfinelinewilfredotorres.bigcartel.com7. CatwomanPaulina Ganucheau – @PlinaGanucheaupaulinaganucheau.tumblr.com8. Donatello, TMNTMaxim Simic – @maximsimicmaximsimic.tumblr.com9. Luchador WerewolfJonah Lobe – @Jonahlobejonahlobe.com10. Cats & the TARDIS, Doctor WhoStaypee – @drstaypeestaypee.tumblr.com11. SheHulkKevin Wada – @kevinwadakevinwada.tumblr.com12. CoralineNan Lawson – @NanLawsonnanlawson.bigcartel.com13. Ms. White, ClueMonica Gallagher – @eatyourlipstickeatyourlipstick.com14. Jason Voorhees, Friday the 13thAdam Gorham – @AdamTGorhamaprincelydreadful.blogspot.com15. Zero, The Nightmare Before ChristmasTaryn – BatmanPaul Gori – @PaulGorigoriart.storenvy.com17. Viv Vision, The VisionMichael Walsh – @Mister_Walshmisterwalsh.tumblr.com18. Lil WerewolfClare Forrest – @idrewthestarsclareforrestillustration.com19. Dog Negan, The Walking DeadNaomi Romero – @NaomiRomeroArtnaomiromero.carbonmade.com20. Shaun & Ed, Shaun of the DeadErin Hunting – @ErinHuntingerinhunting.com21. Otter Warrior: Bertrude the BoldBen Rankel – @benrankelbenrankel.com22. Kirk & Spock, Star Trek II: The Wrath of KhanBlain Hefner – @hefnatronhefnatron.com23. Gandalf, Lord of the RingsRuth Hammond – Margot Tenenbaum, The Royal TenenbaumsJulia Bereciartu – @_juliabejuliabe.com25. Tina Belcher, Bob’s BurgersGrey White – @_GreyWhitegreywhiteart.com26. Eleven, Stranger ThingsEric Merced – @eric_mercedericmerced.com27. WolverineDerek Laufman – @laufmandereklaufman.com28. HellboyShane Hillman – @shanehillmanshanehillman.com29. Warrior & WolfMiquel Rodriguez – @pollomuertopollomuerto.com30. Fauno, Pan’s LabyrinthFilip Ivanovic – @hellsbanditflatbathtub.com31. Creature from the Black LagoonKelly Willaims – @TreeBeerdtreebeerdstuff.comlast_img read more

New study shows why hemecopper oxidases prefer copper over iron

first_img More information: Ambika Bhagi-Damodaran et al. Why copper is preferred over iron for oxygen activation and reduction in haem-copper oxidases, Nature Chemistry (2016). DOI: 10.1038/nchem.2643AbstractHaem–copper oxidase (HCO) catalyses the natural reduction of oxygen to water using a haem-copper centre. Despite decades of research on HCOs, the role of non-haem metal and the reason for nature’s choice of copper over other metals such as iron remains unclear. Here, we use a biosynthetic model of HCO in myoglobin that selectively binds different non-haem metals to demonstrate 30-fold and 11-fold enhancements in the oxidase activity of Cu- and Fe-bound HCO mimics, respectively, as compared with Zn-bound mimics. Detailed electrochemical, kinetic and vibrational spectroscopic studies, in tandem with theoretical density functional theory calculations, demonstrate that the non-haem metal not only donates electrons to oxygen but also activates it for efficient O–O bond cleavage. Furthermore, the higher redox potential of copper and the enhanced weakening of the O–O bond from the higher electron density in the d orbital of copper are central to its higher oxidase activity over iron. This work resolves a long-standing question in bioenergetics, and renders a chemical–biological basis for the design of future oxygen-reduction catalysts. (—A family of enzymes known as heme-copper oxidases (HCOs) plays a pivotal role in the reduction of oxygen into water during cellular respiration. One mystery surrounding heme-copper oxidases is why the non-heme metal center tends to be copper rather than iron. Structure of an enzyme that pathogenic bacteria use to reduce oxygen revealed Explore further Credit: Bhagi-Damodaran, et al Journal information: Nature Chemistry A group of researchers from the University of Illinois, Stevens Institute of Technology, and Oregon Health & Science University has developed a biosynthetic protein model system that replicates the active sites and many structural features of naturally-occurring HCOs. With their model system, they looked at the differences in the reduction of oxygen to water when the non-heme metal is iron versus when it is copper. They found that the non-heme metal plays a key role in electron donation and O-O bond cleavage and that it is likely copper’s d-orbital electron configuration that causes its enhanced activity. Their work appears in Nature Chemistry.”HCOs have been studied for more than half a decade now, but the selection of copper by nature at the nonheme center over other metal ions was not understood,” says lead author Dr. Ambika Bhagi-Damodaran. “Our work is exciting because we finally resolve this long-standing question regarding the structure and function of this very important respiratory enzyme.” Their synthetic analog to the natural heme-copper oxidase is made from myoglobin, a small protein found in muscle that is a cousin to hemoglobin. Myoglobin has an iron-containing heme center and is denoted as FeBMb(FeII) because the heme iron is in the 2+ oxidation state. FeBMb(FeII) was produced and purified without a metal in the non-heme site using a previously reported procedure.The empty FeBMb(FeII) was titrated with ZnII, which is not redox active and serves as the experimental control, CuI, and FeII. Ultraviolet-visible spectroscopy confirmed that each metal was incorporated into the non-heme site. X-ray crystallography confirmed that each of these metal-FeBMb(FeII) variants exhibited similar active sites. In other words, this confirmed that the identity of the non-heme metal did not induce structural changes.Bhagi-Damodaran et al. then investigated the differences in catalytic activity between the iron- and copper-containing species. They looked at reaction rate as well as product selectivity. Their enzymatic assay showed that FeII-FeBMb(FeII) and CuI-FeBMb(FeII) had 11-fold and 30-fold higher oxidase activity compared to the ZnII control and the FeBMb(FeII) without a non-heme metal. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Using electron paramagnetic resonance and X-ray near-edge spectroscopy, they determined that the non-heme CuI was oxidized to CuII and the non-heme FeII was oxidized to FeII, thus confirming that the non-heme metal plays a central role in oxygen reduction as electron donors. To further understand the difference between copper and iron, Bhagi-Damodaran et al. studied the standard reduction potentials (Eo’) of FeIII/FeII and CuII/CuI at the model enzyme site. (The heme iron was replaced with a redox-inactive zinc protoporphyrin using a previously reported protocol.)They found in both species a single reversible wave that corresponded to Eo’ of 259 ± 20mV for iron and Eo’ of 387 ± 25mV for copper. Since standard reduction potentials are related to the thermodynamic driving force of a reaction, copper’s higher value means that CuII/CuI is more efficient at receiving electrons for the electrochemical reduction of oxygen to water.The last step was to look at whether non-heme iron or copper interacts with heme-bound O2 to aid in cleaving the O-O bond. Using resonance Raman spectroscopy, the authors looked at the vibration of the O-O bond and found that the terminal oxygen atom interacts with the nonheme metal weakening the O-O bond. To test if the identity of the nonheme metal had any impact on O-O bond length, the authors performed Density Functional Theory calculations and found that O-O bond length was longest in CuI-FeBMb(FeII). These results showed that the non-heme metal plays an important role in activating the oxygen molecule and facilitating O-O cleavage. The preference of HCOs for copper is likely due to the higher redox potential of Cu as well as its d-orbital electron configuration. Copper-II has nine d-electrons, while FeIII has five d-electrons. This additional electron density gives copper the advantage in orbital interactions with oxygen’s highest occupied molecular orbitals.Overall, this work provides important insights into naturally-occurring heme-copper complexes. According to corresponding author Professor Yi Lu, “We anticipate our work to be a starting point for more focused efforts toward using different metal ions at the non-heme site for various biochemical reactions. This pursuit can aid the design of novel catalysts required in alternative energy technologies and other biotechnological applications.” Citation: New study shows why heme-copper oxidases prefer copper over iron (2016, November 24) retrieved 18 August 2019 from © 2016 Phys.orglast_img read more

Local papaya crops wiped out by flooding

first_imgFelipe Carrillo Puerto, Q.R. — The heavy rains from two recent back-to-back tropical waves have left parts of the south devastated.Residents of Felipe Carrillo Puerto are still without electricity, while farmers in Kantunilkin say water-flooded fields have killed animals and wiped out their crops.Lucio Chuc Sima, president of the papaya producer society in Lázaro Cárdenas says that he has had a total loss in his payapa plantation since the fields remain waterlogged and unsuitable for papaya trees.“We hope that the evaluation of the tour will qualify for damages to support the farmers who have lost one of the main supporters of the local economy,” he said after Juan Castro Loria, a representative with the papaya producers, toured the area.The flooding has caused the loss of other plantations including habanero peppers, watermelon and melon, while others have lost young farm animals such as chickens, pigs, rabbits and turkeys.The Mayan community of Chumpón in the municipality of Felipe Carrillo Puerto is still underwater and without electricity and fresh water after the passing of the tropical waves nearly a week ago.More than 300 homes remain affected by the flooding. On Wednesday, public transportation began running services again from Playa del Carmen into the municipality.Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on WhatsApp (Opens in new window)last_img read more